Over the past year or so, we’ve delved into the data on the UK’s top tech stakeholders, most active VCs, angel networks and corporate venture funds—but what about the entrepreneurs they’re backing?
There’s a whole host of impressive founders behind the scenes of the UK’s top startups and scaleups. In fact, we have profiles on more than 40k founders at ambitious businesses currently tracked on the Beauhurst platform (private UK companies that have hit one or more of our eight triggers). And with our handy Networks add-on, you can even find out who they know through the companies or funds they’re involved with, including who of your own connections.
So now, we’ve taken a closer look at the country’s top serial entrepreneurs—those individuals that have built at least three high-growth UK companies already. This article spotlights a selection of the most active and successful among them, many of whom are now angel investors as well.
Martin Frost
Martin Frost CBE is a serial entrepreneur and business advisor, focusing on the biotech and life sciences space. Most notably, he is the Co-Founder and former CEO of unicorn company CMR Surgical. The surgical robotics firm reached its billion-dollar valuation back in 2019. Frost was awarded his CBE in 2020 for Services to Robotics and British Industry.
Alongside CMR, Frost has co-founded 3D locating and tracking company Omnisense and, more recently, fast-charge battery startup Nyobolt. And he is currently a NED at several other high-growth businesses, including Manchester-based cancer diagnostics firm Zilico and University of Cambridge spinout Sorex Sensors.
As an avid investor himself, Frost is also part of Cambridge Angels, a group of high-net-worth individuals backing early-stage tech companies in the UK. On top of this, he is a member of the advisory panel at Cambridge Innovation Capital, a leading deeptech and life sciences VC firm.
Oriane Chausiaux
Oriane Chausiaux is a French healthtech entrepreneur, who has a PhD in the Genetics of Infertility from the University of Cambridge. Alongside her PhD, in 2006, Chausiaux and her colleagues co-founded Cambridge Temperature Concepts (now Sensiia), successfully developing a new fertility monitoring device, DuoFertility. Since then, Chausiaux has led the Cambridge spinout to secure an impressive 10 equity funding rounds, worth £7.7m in total.
She went on to start Heartfelt Technologies in 2015, as Co-Founder and Chief Scientific Officer. Much like her previous business venture, Heartfelt is based in Cambridge and develops medical devices, but this time focuses on detecting signs of heart failure at home. And most recently, in 2016, Chausiaux founded new venture Cambridge Digital Health, which specialises in app design and development for the healthcare industry.
Alex Chesterman
With two unicorn companies already in his portfolio, Alex Chesterman OBE currently has an estimated £500m+ in private UK shareholdings and 62 directorships to his name. Having previously co-founded DVD rental company LoveFilm in 2003, later bought by Amazon for $200m, Chesterman went on to lead both Zoopla and Cazoo to their billion-dollar valuations.
Chesterman founded proptech firm Zoopla (now ZPG) in 2008, and oversaw its £919m IPO in 2014, before it sold for £2.2b in 2018. Also in 2018, he started Cazoo, an online marketplace for people to buy and sell used cars. Chesterman remains CEO at Cazoo, with the company floating on the NYSE in August 2021, via a $900m SPAC merger with Ajax.
Like many of his peers on this list, Chesterman is also a very active angel investor. He’s backed the likes of Motorway, Secret Escapes, Perkbox, FLOWERBX and Lick. In 2016, he was awarded an OBE for Services to Digital Entrepreneurship.






